SelectiveSweepPat077Bacheleretal2000

30 Nov

Selective sweep in HIV. An NNRTI drug resistance mutation (K103N) goes to fixation in patient virus. The mutation (A to T) apparently occurred on one haplotype (genetic background) and as it went to fixation, genetic variation on was lost. Not all sweeps in HIV are hard sweeps, see next figure.

Selective sweep in HIV. An NNRTI drug resistance mutation (K103N) goes to fixation in patient virus. The mutation (A to T) apparently occurred on one haplotype (genetic background) and as it went to fixation, genetic variation on was lost. Not all sweeps in HIV are hard sweeps, see next figure.

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