With Ben Wilson, Nandita Garud, Alison Feder and Zoe Assaf, I wrote a review paper about population genetics and drug resistance. It was a lot of fun to write this paper and I feel like I learned a lot during the process.
We wrote about drug resistance in influenza, malaria, TB, MRSA and HIV. It turns out that each of these case studies have something unique to teach us about evolution.
The paper is now out in Molecular Ecology. You can also download it here: 2015Wilson_et_al-Molecular_Ecology.
We made five short movies about the paper. Have a look at the one you are most interested in!
Nandita Garud on using genome scans to find resistance loci in malaria
MolEcolNandita from Pleuni Pennings on Vimeo.
Ben Wilson on the role of epistasis in resistance in Influenza
BenMolEcol from Pleuni Pennings on Vimeo.
Pleuni Pennings on standing genetic variation in HIV
MolEcol from Pleuni Pennings on Vimeo.
Alison Feder on clonal interference in TB
MolEcolAlison from Pleuni Pennings on Vimeo.
Zoe Assaf on the origins of the SCCmec element that causes methicillin resistance
MolEcolZoe from Pleuni Pennings on Vimeo.
The CoDE Lab 